Optimization of Multiproduct Batch Plant Design for Protein

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  • OPEN ACCESS Freely available online Drug Designing: Open

    For instance, the design of a multiproduct batch chemical plant is not only to minimize the investment cost, but also to minimize: the operation cost, total production time, and to maximize: the revenue, flexibility index, simultaneously [15]. On the other hand, the key point in the Design of Multiproduct Batch Plants (DMBP) under uncertain demand.

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  • Multiobjective Multiproduct Batch Plant Designud - CORE

    (1992). Evaluation and optimization of stochastic flexibility in multiproduct batch plants. (2002). Optimal design of batch plants with uncertain demands considering switch over of operating modes of parallel units. (2000). Optimal design of protein production plants …

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  • Optimal Design of Protein Production Plants with Time and

    Jan 01, 2000 · In this work we propose an optimization model for the design of a biotechnological multiproduct batch plant. A first level of detail posynomial model is constructed for each unit, as well as decisions regarding the structural optimization of the plant. A particular feature of this model is that it contains composite units in which semicontinuous items operate on the material contained by batch

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  • Multiproduct batch plants design using linear process

    Jan 01, 2011 · Multiproduct batch plants design using linear process performance models Moreno, Marta S.; Montagna, Jorge M. Kefid 00:00:00 In this contribution, a novel linear generalized disjunctive programming (LGDP) model is developed for the design of multiproduct batch plants optimizing both process variables and the structure of the plant through

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  • Optimization of a biotechnological multiproduct batch

    ABSTRACT. In this work a biotechnological multiproduct batch plant that manufactures four different recombinant proteins for human application is described in some detail. This batch plant design is then optimized with regards to the size of equipment using a mixed‐integer linear programming (MILP) formulation recently developed by us in order to find a hypothetical new biotechnological batch plant …

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  • Optimization of Operating Conditions for Protein

    Jan 01, 2009 · In real application, designers not only require to minimize 1105 Multiobjective Multiproduct Batch Plant Design Under Uncertainty: Application to Protein Production investment, but also to minimize the operation cost and horizon time, simultaneously. An example was used to show the significance of the proposed approach.

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  • Optimization of a biotechnological multiproduct batch

    This batch plant design is then optimized with regards to the size of equipment using a mixed‐integer linear programming (MILP) formulation recently developed by us in order to find a hypothetical new biotechnological batch plant based on the information of real known processes for the production of the four recombinant protein products. The real plant was divided for practical purposes into two …

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  • Multiobjective optimization for multiproduct batch plant

    Multiobjective optimization for multiproduct batch plant design under economic and environmental considerations A. Dietz, C. Azzaro-Pantel ∗, L. Pibouleau, S. Domenech Laboratoire de G´enie Chimique-UMR 5503 CNRS/INP/UPS, 5 Rue Paulin Talabot BP1301, 31106 Toulouse Cedex 1, France Abstract This work deals with the multicriteria cost–environment design of multiproduct batch plants, where

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  • Optimization of a biotechnological multiproduct batch

    Optimization of a biotechnological multiproduct batch plant design for the manufacture of four different products: A real case scenario Gabriela Sandoval Centre of Biotechnology and Bioengineering, CeBiB, Department of Chemical Engineering and Biotechnology, University of …

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  • Optimal Design of Protein Production Plants with Time and

    Sep 04, 2008 · In this work we propose an optimization model for the design of a biotechnological multiproduct batch plant. A first level of detail posynomial model is constructed for each unit, as well as decisions regarding the structural optimization of the plant.

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  • Academia.edu - Share research

    Multiobjective Multiproduct Batch Plant Design Under Uncertainty: Application to Protein Production Multiobjective optimal design of a voltage supply inverter fed in-wheel synchronous motor Multiobjective LMI-based controller design for reactive power compensation in a DSTATCOM

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  • Comparison of particle swarm optimization and genetic

    This work deals with the problem of the optimization of multiproduct batch plant design (MBPD) found in a chemical engineering process. The aim of this work is to minimize the investment cost and find out the number and size of parallel equipment units in each stage. For this purpose, it …

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  • A Framework for Multiproduct Batch Plant Design with

    Process performance models for a multiproduct batch protein plant are used to exploit alternative strategies in the optimization of both the process variables and the structure of the plant.

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  • Optimal Design of Multiproduct Batch Plants under

    Oct 27, 2008 · Abstract. In this study, we have introduced a fuzzy decision-making approach to design a multi-objective optimal design problem of a multiproduct batch chemical plant. The design of such plants necessary involves how equipment may be utilized, which means that plant scheduling and production must form an integral part of the design problem.

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  • Comparison of particle swarm optimization and genetic

    5 rows · This work deals with the problem of the optimization of multiproduct batch plant design

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  • Strategies for multiobjective genetic algorithm

    Home Browse by Title Periodicals Computers and Industrial Engineering Vol. 54, No. 3 Strategies for multiobjective genetic algorithm development: Application to optimal batch plant design in process systems engineering

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  • Design of single-product campaign batch plants under

    Find the optimal design of a multiproduct batch plant operat- ing in SPC production mode such that the expected discounted cash flow return (DCFR) of the batch plant, within a prespeci- fied time horizon, is maximized allowing for the optimal adjust- ment of production levels in response to every product demand realization.

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  • Multiobjective optimization for multiproduct batch plant

    Multiobjective optimization for multiproduct batch plant design under economic and environmental considerations A. Dietz, C. Azzaro-Pantel ∗, L. Pibouleau, S. Domenech Laboratoire de G´enie Chimique-UMR 5503 CNRS/INP/UPS, 5 Rue Paulin Talabot BP1301, 31106 Toulouse Cedex 1, France Abstract This work deals with the multicriteria cost–environment design of multiproduct batch plants, where

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  • Dynamic Optimization in the Design and Scheduling of

    Dynamic batch processing provides additional transient operating freedom, that can stretch the limits of profitability under strict market, facility, and time constraints. This paper incorporates dynamic processing conditions for products in a multiproduct batch plant, as opposed to fixing the process by recipes, in the broader context of equipment design, production planning, scheduling, and

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  • Optimization of Multiproduct Batch Plant Design for

    Optimization of Multiproduct Batch Plant Design for Protein Production Using Gradient Boosting Algorithms Youness El Hamzaoui 1*, Juan Antonio Álvarez Arellano 2 This work deals with the problem of modeling and prediction of compressive strength of concrete structure in multiproduct batch plant design of protein …

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